Friday, July 26, 2013

VIDEO: Raw: Gulf of Mexico Gas Well Blowout

A fire broke out on a gas well in the Gulf of Mexico late Tuesday, hours after dozens of workers were evacuated due to an out-of-control leak. No injuries are reported. Officials haven?t said how or when they?ll attempt to put out the blaze. (July 24)

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Source: http://uploadliberty.com/video-raw-gulf-of-mexico-gas-well-blowout/

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Tuesday, June 25, 2013

Texas senator filibusters against abortion bill

AUSTIN, Texas (AP) ? Wearing pink tennis shoes to prepare for nearly 13 consecutive hours of standing, a Democratic Texas state senator on Tuesday began a one-woman filibuster to block a GOP-led effort that would impose stringent new abortion restrictions across the nation's second-most populous state.

Sen. Wendy Davis, 50, of Fort Worth began the filibuster at 11:18 a.m. CDT Tuesday and passed the halfway mark in her countdown to midnight ? the deadline for the end of the 30-day special session.

Rules stipulate she remain standing, not lean on her desk or take any breaks ? even for meals or to use the bathroom. Colleagues removed her chair so she wouldn't sit down by mistake.

If signed into law, the measures would close almost every abortion clinic in Texas, a state 773 miles wide and 790 miles long with 26 million people. A woman living along the Mexico border or in West Texas would have to drive hundreds of miles to obtain an abortion if the law passes.

In her opening remarks, Davis said she was "rising on the floor today to humbly give voice to thousands of Texans" and called Republican efforts to pass the bill a "raw abuse of power."

Democrats chose Davis to lead the effort because of her background as a woman who had her first child as a teenager and went on to graduate from Harvard Law School.

In the hallway outside the Senate chamber, hundreds of women stood in line, waiting for people in the gallery to give up their seats. Women's rights supporters wore orange t-shirts to show their support for Davis, and Lt. Gov. David Dewhurst had to remind those in the gallery that interrupting the proceedings could results in 48 hours in jail.

To stay sharp, Davis slowly circled her desk, pausing occasionally to read from a large binder on her desk. When a male protester stood in the Senate gallery and shouted, "abortion is genocide," Davis continued talking uninterrupted as the man was removed by security.

If the filibuster succeeds, it could also take down other measures. A proposal to fund major transportation projects as well as a bill to have Texas more closely conform with a recent U.S. Supreme Court decision banning mandatory sentences of life in prison without parole for offenders younger than 18 might not get votes. Current state law only allows a life sentence without parole for 17-year-olds convicted of capital murder.

Twice in the first six hours, anti-abortion lawmakers questioned her about the bills, presenting their arguments that the measure will protect women or that abortions were wrong. Davis answered their questions, but did not give up control of the floor as she stood next to her desk.

"This is really about women's health," said Sen, Bob Deuell, who introduced a requirement that all abortions take place in surgical centers, "Sometimes bad things can happen."

Davis questioned then why vasectomies and colonoscopies aren't also required to take place in such clinics.

"Because I've been unable to have a simple question answered to help me understand how this would lead to better care for women, I must question the underlying motive for doing so."

Davis used up large chunks of time reading into the record testimony from women and doctors who would be impacted by the changes, but were denied the opportunity to testify in a Republican-controlled committee because the chairman said the it was becoming repetitive.

During one heart-wrenching story describing a woman's difficult pregnancy, Davis choked up several times and wiped tears, but kept reading.

A petite woman who stays in shape by jogging and cycling, Davis tried to stay comfortable and sharp by shifting her weight from hip to hip and slowly walking around her desk while reading notes from a large binder on her desk.

Republicans watched her closely for any rules slipup that would allow them to break the filibuster and call the bill for a vote.

The bill would ban abortion after 20 weeks of pregnancy and force many clinics that perform the procedure to upgrade their facilities and be classified as ambulatory surgical centers. Also, doctors would be required to have admitting privileges at a hospital within 30 miles ? a tall order in rural communities.

"If this passes, abortion would be virtually banned in the state of Texas, and many women could be forced to resort to dangerous and unsafe measures," said Cecile Richards, president of Planned Parenthood Action Fund and daughter of the late former Texas governor Ann Richards.

Sen. Dan Patrick, R-Houston, said the Democrats never should have been allowed to put Republicans "in a box" and complained that many in the Senate GOP were "flying by the seat of their pants."

But the bill's bogging down began with Republican Gov. Rick Perry, who summoned lawmakers back to work immediately after the regular legislative session ended May 27 but didn't add abortion to the special session to-do list until late in the process. The Legislature can only take up issues at the governor's direction.

Then, House Democrats succeeded in stalling nearly all night Sunday, keeping the bill from reaching the Senate until 11 a.m. Monday.

Debate in that chamber ranged from lawmakers waving coat-hangers on the floor and claiming the new rules are so draconian that women are going to be forced to head to drug war-torn Mexico to have abortions.

At one point, the bill's sponsor, Republican Rep. Jodie Laubenberg of Spring, errantly suggested that emergency room rape kits could be used to terminate pregnancies.

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Senate Bill 5: http://www.legis.state.tx.us/BillLookup/history.aspx?LegSess=831&Bill=SB5

___

Follow Chris Tomlinson on Twitter: http://twitter.com/cltomlinson

Source: http://news.yahoo.com/texas-senator-filibusters-against-abortion-bill-164526586.html

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Monday, June 24, 2013

Two mutations triggered an evolutionary leap 500 million years ago

June 24, 2013 ? Evolution, it seems, sometimes jumps instead of crawls. A research team led by a University of Chicago scientist has discovered two key mutations that sparked a hormonal revolution 500 million years ago.

In a feat of "molecular time travel," the researchers resurrected and analyzed the functions of the ancestors of genes that play key roles in modern human reproduction, development, immunity and cancer. By re-creating the same DNA changes that occurred during those genes' ancient history, the team showed that two mutations set the stage for hormones like estrogen, testosterone and cortisol to take on their crucial present-day roles.

"Changes in just two letters of the genetic code in our deep evolutionary past caused a massive shift in the function of one protein and set in motion the evolution of our present-day hormonal and reproductive systems," said Joe Thornton, PhD, professor of human genetics and ecology & evolution at the University of Chicago, who led the study.

"If those two mutations had not happened, our bodies today would have to use different mechanisms to regulate pregnancy, libido, the response to stress, kidney function, inflammation, and the development of male and female characteristics at puberty," Thornton said.

The findings were published online June 24 in the Proceedings of the National Academy of Sciences.

Understanding how the genetic code of a protein determines its functions would allow biochemists to better design drugs and predict the effects of mutations on disease. Thornton said the discovery shows how evolutionary analysis of proteins' histories can advance this goal, Before the group's work, it was not previously known how the various steroid receptors in modern species distinguish estrogens from other hormones.

The team, which included researchers from the University of Oregon, Emory University and the Scripps Research Institute, studied the evolution of a family of proteins called steroid hormone receptors, which mediate the effects of hormones on reproduction, development and physiology. Without receptor proteins, these hormones cannot affect the body's cells.

Thornton's group traced how the ancestor of the entire receptor family -- which recognized only estrogens -- evolved into descendant proteins capable of recognizing other steroid hormones, such as testosterone, progesterone and the stress hormone cortisol.

To do so, the group used a gene "resurrection" strategy. They first inferred the genetic sequences of ancient receptor proteins, using computational methods to work their way back up the tree of life from a database of hundreds of present-day receptor sequences. They then biochemically synthesized these ancient DNA sequences and used molecular assays to determine the receptors' sensitivity to various hormones.

Thornton's team narrowed down the time range during which the capacity to recognize non-estrogen steroids evolved, to a period about 500 million years ago, before the dawn of vertebrate animals on Earth. They then identified the most important mutations that occurred during that interval by introducing them into the reconstructed ancestral proteins. By measuring how the mutations affected the receptor's structure and function, the team could re-create ancient molecular evolution in the laboratory.

They found that just two changes in the ancient receptor's gene sequence caused a 70,000-fold shift in preference away from estrogens toward other steroid hormones. The researchers also used biophysical techniques to identify the precise atomic-level mechanisms by which the mutations affected the protein's functions. Although only a few atoms in the protein were changed, this radically rewired the network of interactions between the receptor and the hormone, leading to a massive change in function.

"Our findings show that new molecular functions can evolve by sudden large leaps due to a few tiny changes in the genetic code," Thornton said. He pointed out that, along with the two key changes in the receptor, additional mutations, the precise effects of which are not yet known, were necessary for the full effects of hormone signaling on the body to evolve.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/eBlUGA6HrNo/130624152617.htm

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Would anyone care if 'Mad Men's' Don died?

TV

18 hours ago

Falling man from opening of AMC's "Mad Men."

AMC

Falling man from opening of AMC's "Mad Men."

We have a perfect ending for "Mad Men's" season finale: Don Draper jumping out the window.

Obviously there's no chance of that happening. He's the star of the show, and besides, two season-ending suicides in a row (RIP, Lane Pryce) would be awfully repetitive. (Like juggling two juice accounts. RIP, Ocean Spray.)

But nothing is more redundant than Don Draper himself. Other than his brief interlude as a faithful newlywed, you just can't teach this dog new tricks.

Even a year ago, the thought of losing Don would have been inconceivable -- even though the businessman's freefall in the opening title sequence seems to imply that is his ultimate fate. Yeah, yeah, yeah, it's a metaphor, we get it. But the wretched ad exec has become so dull, predictable and dislikable that we really wouldn't miss him if he took a shortcut down to Madison Ave.

Everyone with sense agrees that Jon Hamm is a nearly perfect human creature, but we'd much rather see him in another role -- like his hilarious bubble boy Drew on "30 Rock." And you know what? "Mad Men's" ensemble cast would be just fine without him -- especially Roger Sterling and Sally Draper, who could easily front their own spin-off series.

Here are all the reasons we're over Don Draper:

Serial cheating: He's not unique among his colleagues at Sterling Cooper & Partners, but at least infidelity isn't a full-time hobby for Roger, Pete, Ted (maybe) and the gang. And yes, we know it's a manifestation of Dick Whitman's childhood in a whorehouse, but the backstory doesn't make his adultery any less boring.

Alcoholism: Another snoozer story line. But would Don be more interesting if he were sober? Doubtful. Another Roger acid trip, on the other hand ...

The sads: He wept on Peggy's shoulder and curled up in a fetal position on his disgusted daughter's bed, but we have lost all sympathy for depressed Don. In fact, our reaction is the same as his: Wah, wah, wah.

Tyranny: Don really is a monster, as Peggy called him after he humiliated her and Ted in the season's penultimate episode. He's spiteful, insensitive and downright cruel. So is Pete Campbell -- but at least we love to hate the snarky stair-tumbler. Don we just hate.

Impostor: Once upon a time, Don's identify theft was a thrilling narrative. Now nearly everyone knows the truth, and no one seems to care. Sterling Cooper's creative director works about five minutes a day, is trashed or asleep the rest of the time, insults his clients and colleagues and betrays his family. So why haven't they publicly outed him? Not that we'd really care. Bob Benson's fraud is so much more fascinating now.

Grim Reaper: Don isn't directly to blame for all the show's deaths, but they sure do seem to follow him like Pig Pen's cloud of dirt. And speculation is rampant that Megan might be the next to go, thanks to a number of clues connecting her to Charles Manson victim Sharon Tate. (Megan's obsession with "Rosemary's Baby" -- directed by Tate's husband, Roman Polanski -- only added fuel to the fire.) Her murder would paradoxically breathe new life into "Mad Men" -- but not if it means we'll be subjected to a final season devoted to her widower's grief.

Are you ready for Don to take a flying leap (literally or figuratively)? What do you hope to see in the season finale? Click on "Talk about it" below and share your thoughts!

Source: http://www.today.com/entertainment/if-don-draper-died-mad-men-finale-would-anyone-care-6C10382406

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Development of nonvolatile liquid anthracenes for facile full-color luminescence tuning: Application to foldable light-emitting devices expected

June 23, 2013 ? A research team headed by Dr. Takashi Nakanishi, a Principal Researcher of the NIMS Organic Materials Group, Polymer Materials Unit, developed a full-colour tunable luminescent liquid material with excellent light stability based on an anthracene molecule, which is a general organic fluorescent dye.

A research team headed by Dr. Takashi Nakanishi, a Principal Researcher of the Organic Materials Group (Group Leader: Masayuki Takeuchi), Polymer Materials Unit (Unit Director: Izumi Ichinose) of the National Institute for Materials Science (President: Sukekatsu Ushioda), developed a full-colour tunable luminescent liquid material with excellent photostability based on anthracene, which is a general organic fluorescent dye.

In the development of full-colour display monitors, mobile devices, and other electronic devices, organic molecular and polymer materials are essentially important, as they offer advantages such as light weight, flexibility, and printability. However, in virtually all cases, the light-emitting organic molecular materials developed until now have had difficulties to demonstrate their inherent luminescent performance due to various problems, which include low photostability (durability to prevent discoloration or decolorization under photoirradiation) and aggregation of molecules in the coating process. Moreover, from the viewpoint of production of flexible devices, materials should be free of deterioration of the continuous emissive layer, even when subjected to excessive bending and folding. On the other hand, development of organic molecular materials which enable simple, low-cost manufacture of full-colour luminescence devices, in comparison with individual synthesis of organic molecular materials that display various luminescent colours, is also desired.

The team led by Dr. Nakanishi developed a blue-emitting liquid material which is free of aggregation among adjacent anthracene parts, has a melting point of approximately -60 ?C, and is thermally stable up to about 300 ?C, by attaching highly flexible branched alkyl chains around an anthracene core moiety, which is a fluorescent general dye molecule. This material is a low-viscosity liquid with viscosity of approximately 0.3 Pa-s at room temperature and is a blue-emitting with an absolute fluorescence quantum yield of ca. 55% and photostable more than 5~10 times longer lifetime than that of commercially-available anthracene dyes. Furthermore, because other luminescent dye molecules can be doped homogeneously in this liquid, it was found that full-colour luminescence tuning is available assisted by up to 96% fluorescence resonance energy transfer (FRET) of dyes by single blue-light (365nm) excitation.

In this research, a blue-emitting anthracene liquid with excellent photostability was synthesized, and a liquid material which displays high quality full-colour luminescence and precise luminescence tuning by the facile operation of doping the liquid with other dyes was developed. Since the nonvolatile liquid material developed in this work can be coated on the surface of various substrates, production of organic multicolour devices with stable single color excitation can be expected. A continuous active emitting layer can be maintained, without breaking or interruption even when bent and folded, which is a favorable property for the development of foldable flexible devices.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/wiw-4VNFXlY/130623153502.htm

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'Mad Men's' Don Draper: Sexy, but so sad

TV

18 hours ago

Image: Don Draper

Michael Yarish / AMC

Don Draper found himself surrounded by people, yet all alone and sad, in the ninth episode of the season, titled "Better Half."

It's been a long, sad season for Don Draper on "Mad Men." It seemed almost every episode featured at least one shot of the handsome ad man brooding -- and in some cases, even shedding a tear or two.

What's he got to cry about, you say? We hear you: He's a rich, very successful, good-looking guy with a gorgeous wife. As far as viewers can see, he's still got his health too. (At least, we think so. His liver hasn't started failing from all that drinking yet, right?) So why the long face, Don?

Turns out maybe we should cut the guy a little slack. Money and good looks can't buy happiness, after all. (Just a lot of other stuff that makes life a bit easier.)

Dumped
Nobody tells Don Draper what's what! Unless you're his neighbor/mistress, apparently. In the episode titled "Man With a Plan," the ad man does his own version of "50 Shades of Grey" and orders lover Sylvia to stay in her hotel room all day (although it felt more like days), even taking away her book at one point. By the end of that ordeal, she'd had an epiphany and dumped him. His response? Disbelief. Sad face. Begging. And later, more begging on the phone.

Who are you?
Daughter Sally delivered a knife to Don's -- and viewers' -- hearts this year. After the Draper residence is burgled while the adults are away and Sally was left behind to watch her little brothers, she explained to Don why she was duped into believing the thief -- a black woman -- was her grandma. "She said she knew you," Sally told her dad on the phone later. "I asked her everything I know and she had an answer for everything. Then I realized I don't know anything about you." Sad, ponderous face.

All by himself
Don's often surrounded by people, whether he's at the office, having a meal with clients or enjoying a little tryst with someone. When he hooked up with ex-wife Betty while visiting son Bobby at camp, he admitted that he'd missed her, hinting at how unhappy he is in his current marriage. "Why is sex the definition of being close to someone?" he asked. Her reply? "I don't know. But it is for me, it is for most people." Cue the sad face. And by the next morning, they were miles apart again. As Don headed into the diner for breakfast, he saw Betty sitting with her husband, Henry ... and Don shuffled off to sit alone.

Drowning
After smoking some hashish at a Hollywood party, Don started to hallucinate first the happy, then the sad. The vision of a pregnant Megan came to him first, then Dinkins, the soldier he met in the season premiere. Except now, the young man is missing an arm -- and is dead. "Dying doesn't make you whole," Dinkins told Don when asked why the deceased vet was still missing his appendage in the afterlife. "You should see what you look like." And what does the ad man look like? Depressed. And dead. Floating in a pool face-down dead. But fortunately for him, the dead part was a hallucination, but he really was drowning in the pool until Roger dove in and saved him.

Busted
When Don finally got caught cheating with Sylvia, it wasn't by who viewers -- or Don himself -- were probably expecting. It was Sally who walked in on the two lovebirds. This sent Don first into panic mode, which eventually morphed into depression. It became obvious two episodes later, when Don started out the penultimate episode of the season curled up in a fetal position on Sally's bed, and ended the hour the same way, realizing that his actions have cost him a relationship with his little girl.

What Sunday's finale holds for Don's happiness, you'll have to tune in and see at 10 p.m. on AMC.

Source: http://www.today.com/entertainment/mad-mens-don-draper-sexy-successful-so-sad-6C10367555

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